Item Type | Name |
Concept
|
Acclimatization
|
Concept
|
Adaptation, Biological
|
Concept
|
Haplorhini
|
Concept
|
Adaptation, Physiological
|
Concept
|
Blood Flow Velocity
|
Concept
|
Hypoxia
|
Concept
|
Antineoplastic Combined Chemotherapy Protocols
|
Concept
|
Chromosomes, Human, Pair 2
|
Concept
|
Pan troglodytes
|
Concept
|
Birth Weight
|
Concept
|
Body Temperature Regulation
|
Concept
|
Ecology
|
Concept
|
Biopsy
|
Concept
|
Evaluation Studies as Topic
|
Concept
|
Biological Evolution
|
Concept
|
Chromosomes, Human, Pair 1
|
Concept
|
Cold Climate
|
Concept
|
Cell Cycle
|
Concept
|
Chromosomes, Human, Pair 14
|
Concept
|
Chromosome Mapping
|
Concept
|
Chromosomes, Human, Pair 4
|
Concept
|
Crossing Over, Genetic
|
Concept
|
Hemoglobins
|
Concept
|
Hepatitis B Antigens
|
Concept
|
Hepatitis B e Antigens
|
Concept
|
Demography
|
Concept
|
Homozygote
|
Concept
|
Consanguinity
|
Concept
|
DNA-Binding Proteins
|
Concept
|
Drug Synergism
|
Concept
|
Cytochrome P-450 Enzyme System
|
Concept
|
Child, Preschool
|
Concept
|
DNA Mutational Analysis
|
Concept
|
DNA, Recombinant
|
Concept
|
Electrophoresis, Polyacrylamide Gel
|
Concept
|
Glucocorticoids
|
Concept
|
Hemoglobin, Sickle
|
Concept
|
Hemoglobinopathies
|
Concept
|
Hepatitis B Antibodies
|
Concept
|
Hylobates
|
Concept
|
Hypertension
|
Concept
|
Drug Resistance
|
Concept
|
Electrophoresis, Cellulose Acetate
|
Concept
|
Environment
|
Concept
|
Gene Expression Regulation
|
Concept
|
Gene Pool
|
Concept
|
Gene Conversion
|
Concept
|
Fasting
|
Concept
|
Neovascularization, Pathologic
|
Concept
|
Nucleic Acid Hybridization
|
Concept
|
Geography
|
Concept
|
Immune Tolerance
|
Concept
|
Energy Metabolism
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
Concept
|
Hepatitis B
|
Concept
|
Fourier Analysis
|
Concept
|
Gene Amplification
|
Concept
|
Genetics, Medical
|
Concept
|
Genetics, Population
|
Concept
|
Hemoglobin H
|
Concept
|
Pharmacogenetics
|
Concept
|
Pilot Projects
|
Concept
|
Pongo pygmaeus
|
Concept
|
Pregnancy
|
Concept
|
Prenatal Diagnosis
|
Concept
|
Prions
|
Concept
|
Organ Culture Techniques
|
Concept
|
Recombination, Genetic
|
Concept
|
Mutation
|
Concept
|
Nutritional Physiological Phenomena
|
Concept
|
Selection, Genetic
|
Concept
|
Pedigree
|
Concept
|
Mammography
|
Concept
|
Phytohemagglutinins
|
Concept
|
Stress, Physiological
|
Concept
|
Polymorphism, Genetic
|
Concept
|
Female
|
Concept
|
Fetal Hemoglobin
|
Concept
|
Taste
|
Concept
|
Phenobarbital
|
Concept
|
Population Surveillance
|
Concept
|
Prostatic Neoplasms
|
Concept
|
Primates
|
Concept
|
Protein Precursors
|
Concept
|
Protein Binding
|
Concept
|
Protein Conformation
|
Concept
|
Pseudogenes
|
Concept
|
Proteins
|
Concept
|
Genetic Markers
|
Concept
|
HLA Antigens
|
Concept
|
Haplotypes
|
Concept
|
Sequence Homology, Nucleic Acid
|
Concept
|
Species Specificity
|
Concept
|
Cohort Studies
|
Concept
|
Polymorphism, Restriction Fragment Length
|
Concept
|
Skin Pigmentation
|
Concept
|
Hemodynamics
|
Concept
|
Hemoglobins, Abnormal
|
Concept
|
Homeostasis
|
Concept
|
Humans
|
Concept
|
Transcription, Genetic
|
Concept
|
Sequence Homology, Amino Acid
|
Concept
|
Genetic Variation
|
Concept
|
Ultraviolet Rays
|
Concept
|
Germ-Line Mutation
|
Concept
|
Histocompatibility Antigens Class I
|
Concept
|
Male
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
Concept
|
Multifactorial Inheritance
|
Concept
|
Gene Duplication
|
Concept
|
Uridine Phosphorylase
|
Concept
|
Protein Subunits
|
Concept
|
Water-Electrolyte Balance
|
Concept
|
NF-kappa B
|
Concept
|
Principal Component Analysis
|
Concept
|
Gene Products, env
|
Concept
|
HIV Envelope Protein gp120
|
Concept
|
Prevalence
|
Concept
|
Mutagenesis
|
Concept
|
Meiosis
|
Concept
|
NAD(P)H Dehydrogenase (Quinone)
|
Concept
|
DNA Probes
|
Concept
|
Paclitaxel
|
Concept
|
Gene Expression
|
Concept
|
Sequence Alignment
|
Concept
|
Case-Control Studies
|
Concept
|
Human Genome Project
|
Concept
|
Alternative Splicing
|
Concept
|
Sequence Analysis, DNA
|
Concept
|
Ecosystem
|
Concept
|
Bronchial Hyperreactivity
|
Concept
|
RNA-Binding Proteins
|
Concept
|
Immediate-Early Proteins
|
Concept
|
Cell Proliferation
|
Concept
|
Evolution, Molecular
|
Concept
|
Founder Effect
|
Concept
|
Gene Regulatory Networks
|
Concept
|
Drosophila Proteins
|
Concept
|
Biomarkers, Pharmacological
|
Concept
|
Genetic Association Studies
|
Concept
|
Mitochondrial Proteins
|
Concept
|
Paleodontology
|
Concept
|
Gene-Environment Interaction
|
Concept
|
Receptors, G-Protein-Coupled
|
Concept
|
Proto-Oncogene Proteins c-mdm2
|
Concept
|
Chromatin Immunoprecipitation
|
Concept
|
Neovascularization, Physiologic
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
Concept
|
Base Pairing
|
Concept
|
Gene Expression Profiling
|
Concept
|
Plasmodium vivax
|
Concept
|
Pigmentation
|
Concept
|
Plasmodium falciparum
|
Concept
|
Population Density
|
Concept
|
Population Dynamics
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
Gene Flow
|
Concept
|
Recombinant Proteins
|
Concept
|
Radioimmunoassay
|
Concept
|
Mechanotransduction, Cellular
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Epidemiologic Research Design
|
Concept
|
Down-Regulation
|
Concept
|
DNA Copy Number Variations
|
Concept
|
Transfection
|
Concept
|
Blotting, Southern
|
Concept
|
Hominidae
|
Concept
|
Prion Diseases
|
Concept
|
Phylogeography
|
Concept
|
Genome, Human
|
Concept
|
Polymerase Chain Reaction
|
Concept
|
DNA Methylation
|
Concept
|
Extinction, Biological
|
Concept
|
Pan paniscus
|
Concept
|
Antimicrobial Cationic Peptides
|
Concept
|
Genetic Heterogeneity
|
Concept
|
HIV Envelope Protein gp160
|
Concept
|
Basic Helix-Loop-Helix Transcription Factors
|
Concept
|
Genome-Wide Association Study
|
Concept
|
Adaptive Immunity
|
Concept
|
Hep G2 Cells
|
Concept
|
Precision Medicine
|
Concept
|
HLA-G Antigens
|
Concept
|
Cytochrome P-450 CYP3A
|
Concept
|
Antineoplastic Agents, Phytogenic
|
Concept
|
Chromatin
|
Concept
|
Chromosomes, Human, Pair 16
|
Concept
|
Climate
|
Concept
|
Electron Transport
|
Concept
|
Electrophoresis, Agar Gel
|
Concept
|
Extrachromosomal Inheritance
|
Concept
|
Genetic Testing
|
Concept
|
Genotype
|
Concept
|
Hepatitis B virus
|
Concept
|
Heterozygote
|
Concept
|
Immunity, Innate
|
Concept
|
Genetic Linkage
|
Concept
|
Lymphocyte Activation
|
Concept
|
Military Personnel
|
Concept
|
Organ Specificity
|
Concept
|
Pakistan
|
Concept
|
Papio
|
Concept
|
Phenotype
|
Concept
|
Phylogeny
|
Concept
|
Placenta
|
Concept
|
Population
|
Concept
|
Predictive Value of Tests
|
Concept
|
Histone-Lysine N-Methyltransferase
|
Concept
|
Signal Transduction
|
Concept
|
HIV-1
|
Concept
|
Transcriptional Activation
|
Concept
|
Gene Expression Regulation, Neoplastic
|
Concept
|
Discriminant Analysis
|
Concept
|
Tumor Suppressor Protein p53
|
Concept
|
DNA Primers
|
Concept
|
Computational Biology
|
Concept
|
Genetic Predisposition to Disease
|
Concept
|
Polymorphism, Single Nucleotide
|
Concept
|
Genomics
|
Concept
|
Genetic Drift
|
Concept
|
Chromosomes, Human, Y
|
Concept
|
History, Ancient
|
Concept
|
NF-kappa B p50 Subunit
|
Concept
|
HapMap Project
|
Academic Article
|
Studies of populations and genetic diseases: mixing it up. Inherited disorders and their genes in different European populations, Acquafredda di Maratea, Italy, 6-11 February 1998.
|
Academic Article
|
Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma.
|
Academic Article
|
Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism.
|
Academic Article
|
Adjusting the focus on human variation.
|
Academic Article
|
Detection of the signature of natural selection in humans: evidence from the Duffy blood group locus.
|
Academic Article
|
Gene conversion and different population histories may explain the contrast between polymorphism and linkage disequilibrium levels.
|
Academic Article
|
Variability at the uridine diphosphate glucuronosyltransferase 1A1 promoter in human populations and primates.
|
Academic Article
|
Complex signatures of natural selection at the Duffy blood group locus.
|
Academic Article
|
Microsatellite mutations and inferences about human demography.
|
Academic Article
|
A population genetics study of single nucleotide polymorphisms in the interleukin 4 receptor alpha (IL4RA) gene.
|
Academic Article
|
Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus.
|
Academic Article
|
Linkage disequilibrium and age estimates of a deletion polymorphism (1597DeltaC) in HLA-G suggest non-neutral evolution.
|
Academic Article
|
Inferences about human demography based on multilocus analyses of noncoding sequences.
|
Academic Article
|
Balancing claims for balancing selection.
|
Academic Article
|
CYP3A variation and the evolution of salt-sensitivity variants.
|
Academic Article
|
Population genetics of CAPN10 and GPR35: implications for the evolution of type 2 diabetes variants.
|
Academic Article
|
Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups.
|
Academic Article
|
Haplotype structure and phylogenetic shadowing of a hypervariable region in the CAPN10 gene.
|
Academic Article
|
An evolutionary framework for common diseases: the ancestral-susceptibility model.
|
Academic Article
|
Interrogating multiple aspects of variation in a full resequencing data set to infer human population size changes.
|
Academic Article
|
Prevalence of common disease-associated variants in Asian Indians.
|
Academic Article
|
Combining sperm typing and linkage disequilibrium analyses reveals differences in selective pressures or recombination rates across human populations.
|
Academic Article
|
Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and breast cancer risk in Africans.
|
Academic Article
|
Comparative linkage-disequilibrium analysis of the beta-globin hotspot in primates.
|
Academic Article
|
Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans.
|
Academic Article
|
UGT2B7 is not expressed in normal breast.
|
Academic Article
|
Functional constraints on the constitutive androstane receptor inferred from human sequence variation and cross-species comparisons.
|
Academic Article
|
Sequence diversity and haplotype structure at the human CYP3A cluster.
|
Academic Article
|
Evolutionary adaptations to dietary changes.
|
Academic Article
|
Comparative genomics analysis of human sequence variation in the UGT1A gene cluster.
|
Academic Article
|
Adaptations to new environments in humans: the role of subtle allele frequency shifts.
|
Academic Article
|
Allelic imbalance (AI) identifies novel tissue-specific cis-regulatory variation for human UGT2B15.
|
Academic Article
|
Population genetic analysis of the uncoupling proteins supports a role for UCP3 in human cold resistance.
|
Academic Article
|
Adaptations to climate-mediated selective pressures in humans.
|
Academic Article
|
Adaptations to climate in candidate genes for common metabolic disorders.
|
Academic Article
|
Adaptive variation regulates the expression of the human SGK1 gene in response to stress.
|
Academic Article
|
SNP discovery, expression and cis-regulatory variation in the UGT2B genes.
|
Academic Article
|
Spatial patterns of variation due to natural selection in humans.
|
Academic Article
|
Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes.
|
Academic Article
|
Characterization of a novel splicing variant in the RAPTOR gene.
|
Academic Article
|
Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency.
|
Academic Article
|
Differential allelic expression of c.1568C > A at UGT2B15 is due to variation in a novel cis-regulatory element in the 3'UTR.
|
Academic Article
|
Mapping gene-environment interactions at regulatory polymorphisms: insights into mechanisms of phenotypic variation.
|
Academic Article
|
Adaptation - not by sweeps alone.
|
Academic Article
|
Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations.
|
Academic Article
|
A reduced representation approach to population genetic analyses and applications to human evolution.
|
Academic Article
|
Sequence diversity at the proximal 14q32.1 SERPIN subcluster: evidence for natural selection favoring the pseudogenization of SERPINA2.
|
Academic Article
|
A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses.
|
Academic Article
|
Reconstructing Native American population history.
|
Academic Article
|
rs2981582 is associated with FGFR2 expression in normal breast.
|
Academic Article
|
A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk.
|
Academic Article
|
Population genetics models of common diseases.
|
Academic Article
|
Using environmental correlations to identify loci underlying local adaptation.
|
Academic Article
|
Natural selection and functional genetic variation in the p53 pathway.
|
Academic Article
|
Lack of association between common UGT2B nonsynonymous single-nucleotide polymorphisms and breast cancer in populations of African ancestry.
|
Academic Article
|
Heterogeneity of microsatellite mutations within and between loci, and implications for human demographic histories.
|
Academic Article
|
Prdm9, a major determinant of meiotic recombination hotspots, is not functional in dogs and their wild relatives, wolves and coyotes.
|
Academic Article
|
Genetic, functional and molecular features of glucocorticoid receptor binding.
|
Academic Article
|
Inter-ethnic differences in lymphocyte sensitivity to glucocorticoids reflect variation in transcriptional response.
|
Academic Article
|
The genetic architecture of adaptations to high altitude in Ethiopia.
|
Academic Article
|
Incomplete lineage sorting is common in extant gibbon genera.
|
Academic Article
|
Allelic imbalance assays to quantify allele-specific gene expression and transcription factor binding.
|
Academic Article
|
Mutational processes of simple-sequence repeat loci in human populations.
|
Academic Article
|
Ethiopian National Hepatitis B Study.
|
Academic Article
|
Adaptations to local environments in modern human populations.
|
Academic Article
|
Toward a more accurate time scale for the human mitochondrial DNA tree.
|
Academic Article
|
In vitro sensitivity assays and clinical response to glucocorticoids in patients with inflammatory bowel disease.
|
Academic Article
|
mtDNA analysis of Nile River Valley populations: A genetic corridor or a barrier to migration?
|
Academic Article
|
Association of Hb H disease with sickle-trait.
|
Academic Article
|
Combining genetic and nongenetic biomarkers to realize the promise of pharmacogenomics for inflammatory diseases.
|
Academic Article
|
Genome mapping by arbitrary amplification of yeast artificial chromosomes.
|
Academic Article
|
Amplification with arbitrary primers.
|
Academic Article
|
Plasma hepcidin of Ethiopian highlanders with steady-state hypoxia.
|
Academic Article
|
Genetic mapping with multiple levels of phenotypic information reveals determinants of lymphocyte glucocorticoid sensitivity.
|
Academic Article
|
Comparison of cellular and transcriptional responses to 1,25-dihydroxyvitamin d3 and glucocorticoids in peripheral blood mononuclear cells.
|
Academic Article
|
Tracing European founder lineages in the Near Eastern mtDNA pool.
|
Academic Article
|
Molecular characterization of beta-thalassemia mutations in Egypt.
|
Academic Article
|
Protection against malaria morbidity: near-fixation of the alpha-thalassemia gene in a Nepalese population.
|
Academic Article
|
Discovery and functional assessment of gene variants in the vascular endothelial growth factor pathway.
|
Academic Article
|
A further case of G gamma-beta + hereditary persistence of Hb F associated to the -202 C----G mutation in the G gamma promoter region.
|
Academic Article
|
Branching pattern in the evolutionary tree for human mitochondrial DNA.
|
Academic Article
|
Frequency of the -alpha 3.7 thalassemia deletion in the non-white Cuban population.
|
Academic Article
|
A case of hereditary persistence of fetal hemoglobin caused by a gene not linked to the beta-globin cluster.
|
Academic Article
|
Admixture facilitates genetic adaptations to high altitude in Tibet.
|
Academic Article
|
The distribution of linkage disequilibrium over anonymous genome regions.
|
Academic Article
|
Frequency and molecular types of deletional alpha-thalassemia in Egypt.
|
Academic Article
|
Excess of rare amino acid polymorphisms in the Toll-like receptor 4 in humans.
|
Academic Article
|
Gene expression of peripheral blood cells reveals pathways downstream of glucocorticoid receptor antagonism and nab-paclitaxel treatment.
|
Academic Article
|
Alpha +-thalassemia haplotypes in Italy.
|
Academic Article
|
Pilot study demonstrating potential association between breast cancer image-based risk phenotypes and genomic biomarkers.
|
Academic Article
|
Molecular basis for HbH disease in Italy: geographical distribution of deletional and nondeletional alpha-thalassemia haplotypes.
|
Academic Article
|
Frequency and types of deletional alpha+-thalassemia in northern Sardinia.
|
Academic Article
|
Molecular characterization of HbH disease in the Cuban population.
|
Academic Article
|
Global diversity, population stratification, and selection of human copy-number variation.
|
Academic Article
|
Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans.
|
Academic Article
|
Deep History of East Asian Populations Revealed Through Genetic Analysis of the Ainu.
|
Academic Article
|
Prevalence of HBeAg, anti-HBe serological markers and HBV-DNA in asymptomatic carriers in Ethiopia.
|
Academic Article
|
Estimating the Ages of Selection Signals from Different Epochs in Human History.
|
Academic Article
|
Different proliferative response of human and chimpanzee lymphocytes after contact with human immunodeficiency virus type 1 gp120.
|
Academic Article
|
Patterns of Transcriptional Response to 1,25-Dihydroxyvitamin D3 and Bacterial Lipopolysaccharide in Primary Human Monocytes.
|
Academic Article
|
Long-term genetic stability and a high-altitude East Asian origin for the peoples of the high valleys of the Himalayan arc.
|
Academic Article
|
Mapping Variation in Cellular and Transcriptional Response to 1,25-Dihydroxyvitamin D3 in Peripheral Blood Mononuclear Cells.
|
Academic Article
|
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations.
|
Academic Article
|
Editorial overview: Genetics of human origin: New horizons in human population genetics.
|
Academic Article
|
Genetic structure in the Sherpa and neighboring Nepalese populations.
|
Academic Article
|
Colonic transcriptional response to 1a,25(OH)2 vitamin D3 in African- and European-Americans.
|
Academic Article
|
Ethnically Tibetan women in Nepal with low hemoglobin concentration have better reproductive outcomes.
|
Academic Article
|
A longitudinal cline characterizes the genetic structure of human populations in the Tibetan plateau.
|
Academic Article
|
The genomic landscape of Nepalese Tibeto-Burmans reveals new insights into the recent peopling of Southern Himalayas.
|
Academic Article
|
The genetic prehistory of the Andean highlands 7000 years BP though European contact.
|
Academic Article
|
Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics.
|
Academic Article
|
Correction: A longitudinal cline characterizes the genetic structure of human populations in the Tibetan plateau.
|
Academic Article
|
Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal.
|
Academic Article
|
Inferring the model and onset of natural selection under varying population size from the site frequency spectrum and haplotype structure.
|
Academic Article
|
Ancient genomes from the Himalayas illuminate the genetic history of Tibetans and their Tibeto-Burman speaking neighbors.
|
Academic Article
|
A pleiotropic hypoxia-sensitive EPAS1 enhancer is disrupted by adaptive alleles in Tibetans.
|
Concept
|
Uncoupling Protein 2
|
Concept
|
Uncoupling Protein 3
|
Concept
|
Uncoupling Protein 1
|
Concept
|
Regulatory-Associated Protein of mTOR
|
Concept
|
Human Migration
|
Concept
|
Hepcidins
|
Concept
|
Hypoxia-Inducible Factor-Proline Dioxygenases
|
Grant
|
Local Adaptations in Humans
|
Grant
|
LINKAGE DISEQUILIBRIUM IN THE HUMAN GENOME
|
Grant
|
Functional Genomics of Tibetan Adaptations
|
Grant
|
Evolutionary Genetics of the Metabolic Syndrome
|
Grant
|
Evolutionary genomics of the vitamin D pathway in humans - Resubmission 01
|